Description

tert-Butyl-[1-(2-Iodo-1-Methyl-Ethyl)-7A-Methyl-Octahydro-Inden-4-Yloxy]-Dimethyl-Silane is a sophisticated organosilicon intermediate featuring a unique sterically hindered structure and an iodine functional group, making it a valuable building block for advanced organic synthesis. This compound is engineered to provide precise molecular architecture for constructing complex molecules, offering chemists a versatile handle for further functionalization. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting complex, polycyclic structures.
• Agrochemical Research: Used in the development of new pesticides and herbicides, where its unique indane-derived scaffold can contribute to specific biological activity.
• Advanced Material Synthesis: Serves as a precursor for creating specialized silicone-based polymers or hybrid organic-inorganic materials with tailored properties.
• Catalyst Ligand Development: The sterically demanding tert-butyldimethylsilyl (TBDMS) and iodomethyl groups make it a candidate for constructing novel ligands in transition metal catalysis.
• Chemical Biology Probes: The iodine atom provides a site for further cross-coupling reactions (e.g., Sonogashira, Suzuki), useful for tagging or modifying biomolecules.
• Process Chemistry & Scale-up: Employed in route scouting and optimization for the commercial production of high-value specialty chemicals.

Basic Information

Product Name	tert-Butyl-[1-(2-Iodo-1-Methyl-Ethyl)-7A-Methyl-Octahydro-Inden-4-Yloxy]-Dimethyl-Silane
CAS No.	214351-86-7
Molecular Formula	C19H37IOSi
Molecular Weight	436.50 g/mol
Synonyms	tert-Butyldimethyl((1-((2-iodopropan-2-yl)-7a-methyloctahydro-1H-inden-4-yl)oxy)silane; 4-((tert-Butyldimethylsilyl)oxy)-1-(2-iodo-1-methylethyl)-7a-methyloctahydro-1H-indene; 1-(2-Iodo-1-methylethyl)-7a-methyloctahydroinden-4-yl tert-butyldimethylsilyl ether; TBDMS Ether of 1-(2-Iodo-1-methylethyl)-7a-methyloctahydroinden-4-ol
EINECS	Contact for details

Quality Control

Our production of tert-Butyl-[1-(2-Iodo-1-Methyl-Ethyl)-7A-Methyl-Octahydro-Inden-4-Yloxy]-Dimethyl-Silane adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is characterized using advanced analytical techniques including NMR, HPLC, and GC-MS. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥ 95.0% (Typical 97-99%)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.