Description

2-[3-Chloro-5-(Trifluoromethyl)-2-Pyridinyl]-2-Phenylacetonitrile is a high-value, multi-functional chemical intermediate featuring a unique trifluoromethylpyridine core. This compound matters for its role as a critical building block in the synthesis of advanced active ingredients, particularly in the agrochemical and pharmaceutical sectors. Industries that require sophisticated chemical synthesis, such as crop protection R&D and fine chemical manufacturing, need this precise intermediate to develop new products with enhanced efficacy and novel modes of action.

Application

• Agrochemical Intermediate: A key precursor in the synthesis of novel herbicides, insecticides, and fungicides, leveraging the bioactivity of the trifluoromethylpyridine moiety.
• Pharmaceutical Building Block: Used in medicinal chemistry for the research and development of new active pharmaceutical ingredients (APIs), especially those targeting central nervous system and metabolic diseases.
• Ligand Synthesis: Serves as a starting material for creating specialized ligands used in catalysis and material science applications.
• Fine Chemical Production: Employed in custom synthesis and contract manufacturing for producing high-value, low-volume specialty chemicals.
• Research & Development: Essential for academic and industrial R&D labs exploring new chemical entities and reaction pathways in heterocyclic chemistry.

Basic Information

Product Name	2-[3-Chloro-5-(Trifluoromethyl)-2-Pyridinyl]-2-Phenylacetonitrile
CAS No.	213994-27-5
Molecular Formula	C14H8ClF3N2
Molecular Weight	296.67 g/mol
Synonyms	2-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-2-phenylacetonitrile; α-Phenyl-3-chloro-5-(trifluoromethyl)picolinonitrile; 2-Phenyl-2-[3-chloro-5-(trifluoromethyl)-2-pyridyl]acetonitrile; 3-Chloro-5-(trifluoromethyl)picolinonitrile, α-phenyl-; (3-Chloro-5-trifluoromethyl-pyridin-2-yl)-phenyl-acetonitrile
EINECS	Contact for details

Quality Control

Our 2-[3-Chloro-5-(Trifluoromethyl)-2-Pyridinyl]-2-Phenylacetonitrile is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes rigorous analytical testing, including HPLC for assay and purity determination, to meet exacting customer specifications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.