Description

N,n-Dimethyl-4-(4,5,6,7-Tetrahydrothieno[3,2-C]Pyridin-4-Yl)Benzenamine is a high-purity, advanced pharmaceutical intermediate of significant commercial and research interest. Its core value lies in its role as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly in the cardiovascular and central nervous system therapeutic areas. This compound is essential for manufacturers and R&D laboratories focused on developing novel small-molecule drugs and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of clopidogrel and other thienopyridine-class antiplatelet agents.
• API Synthesis: Used in the multi-step manufacturing process of active pharmaceutical ingredients targeting P2Y12 receptor antagonism.
• Cardiovascular Drug Research: Serves as a critical scaffold in R&D for new antithrombotic and antiplatelet medications.
• Fine Chemical Production: Employed in the custom synthesis of complex, high-value organic molecules for specialized applications.
• Biochemical Research: Used as a reference standard or building block in pharmacological and metabolic studies.
• Process Development: Utilized by chemical engineers for scaling up and optimizing synthetic routes for commercial drug production.

Basic Information

Product Name	N,n-Dimethyl-4-(4,5,6,7-Tetrahydrothieno[3,2-C]Pyridin-4-Yl)Benzenamine
CAS No.	213462-04-5
Molecular Formula	C15H18N2S
Molecular Weight	258.38 g/mol
Synonyms	4-(4,5,6,7-Tetrahydrothieno[3,2-c]pyridin-4-yl)-N,N-dimethylaniline; Clopidogrel Intermediate; 4-(Dimethylamino)benzyl-4,5,6,7-tetrahydrothieno[3,2-c]pyridine; SR 25989 intermediate; 2-(2-Chlorophenyl)-2-(4,5,6,7-tetrahydrothieno[3,2-c]pyrid-4-yl)acetic acid methyl ester precursor; Methyl (2-chlorophenyl)(4,5,6,7-tetrahydrothieno[3,2-c]pyridin-4-yl)acetate intermediate; 2-Chloro-α-(4,5,6,7-tetrahydrothieno[3,2-c]pyridin-4-yl)acetic acid methyl ester related compound.
EINECS	Contact for details

Quality Control

Our N,n-Dimethyl-4-(4,5,6,7-Tetrahydrothieno[3,2-C]Pyridin-4-Yl)Benzenamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. Production can be aligned with cGMP guidelines for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.