Description

(S)-2-Cyclohexylsuccinic Acid-1-Methyl Ester is a high-purity chiral building block and synthetic intermediate of significant commercial interest. Its defined stereochemistry and functional group versatility make it a critical precursor in the development of active pharmaceutical ingredients (APIs) and advanced fine chemicals. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to incorporate a chiral cyclohexyl moiety into complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the asymmetric synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of chiral pesticides and herbicides, where stereochemistry can significantly influence biological activity and environmental safety.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing chiral ligands and organocatalysts used in enantioselective transformations.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances requiring high enantiomeric purity.
• Academic and R&D: A valuable reagent for methodological development in organic synthesis and medicinal chemistry research within university and corporate laboratories.

Basic Information

Product Name	(S)-2-Cyclohexylsuccinic Acid-1-Methyl Ester
CAS No.	213270-44-1
Molecular Formula	C11H18O4
Molecular Weight	214.26 g/mol
Synonyms	(S)-1-Methyl 2-cyclohexylsuccinate; (S)-Methyl 2-cyclohexylsuccinate; (S)-2-(Cyclohexyl)butanedioic acid 1-methyl ester; (S)-Cyclohexylsuccinic acid monomethyl ester; (S)-2-Cyclohexyl-1,4-butanedioic acid 1-methyl ester; (S)-Methyl hydrogen 2-cyclohexylsuccinate; (S)-2-Cyclohexylsuccinic acid methyl ester
EINECS	Contact for details

Quality Control

Our (S)-2-Cyclohexylsuccinic Acid-1-Methyl Ester is produced under strict quality management systems to ensure batch-to-batch consistency and high enantiomeric purity. We provide comprehensive Certificates of Analysis (COA) for each batch, detailing parameters such as chiral purity (enantiomeric excess), chemical purity (by HPLC), and identity confirmation. Our quality commitment aligns with the standards required for cGMP and non-GMP pharmaceutical intermediate applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.