Description

(R)-2-(2-Naphthylmethyl)Succinic Acid-1-Methyl Ester, 95%, (98% E.E.) is a high-purity chiral building block of significant importance in asymmetric synthesis. Its value lies in the high enantiomeric excess (98% E.E.), which is critical for producing optically active intermediates with defined stereochemistry. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and fine chemicals.

Application

This chiral ester serves as a versatile intermediate in sophisticated organic synthesis. Key application areas include:

• Pharmaceutical Intermediate: Synthesis of chiral drug candidates and active pharmaceutical ingredients (APIs) requiring specific (R)-configuration.
• Asymmetric Catalyst Ligand Precursor: Building block for the development of novel chiral ligands used in catalytic asymmetric reactions.
• Fine Chemical Synthesis: Production of high-value, optically pure specialty chemicals for agrochemical and material science research.
• Academic & Industrial R&D: Use in method development and exploratory chemistry for creating new molecular entities with targeted properties.

Basic Information

Product Name	(R)-2-(2-Naphthylmethyl)Succinic Acid-1-Methyl Ester, 95%, (98% E.E.)
CAS No.	213270-42-9
Molecular Formula	C₁₆H₁₆O₄
Molecular Weight	272.30 g/mol
Synonyms	(R)-1-Methoxy-1-oxo-4-(naphthalen-2-ylmethyl)butan-2-yl acetate (related form); Methyl (R)-2-((2-naphthyl)methyl)succinate; (R)-2-(2-Naphthylmethyl)butanedioic acid 1-methyl ester; (2R)-2-[(Naphthalen-2-yl)methyl]butanedioic acid methyl ester; Succinic acid, 2-(2-naphthylmethyl)-, 1-methyl ester, (R)-; Chiral naphthylmethyl succinate ester; (R)-Methyl 2-(naphthalen-2-ylmethyl)succinate
EINECS	Contact for details

Quality Control

This product is manufactured under strict quality control protocols to ensure batch-to-batch consistency. The specified 95% chemical purity and 98% enantiomeric excess are verified using advanced analytical techniques including HPLC and chiral chromatography. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and chiral purity is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.