Description

Morpholine-3,4-Dicarboxylic Acid 4-tert-Butyl Ester 3-Methyl Ester is a high-purity, synthetically valuable building block used in advanced organic synthesis. This compound is critical for researchers and manufacturers developing novel active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily utilized by the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of complex drug candidates, particularly those targeting the central nervous system.
• Agrochemical Research: Used as a precursor for developing novel herbicides, fungicides, and insecticides with specific stereochemical requirements.
• Ligand Synthesis: Serves as a starting material for creating sophisticated chiral ligands used in asymmetric catalysis.
• Peptidomimetics: Incorporated into the backbone of peptide-like molecules to enhance metabolic stability and bioavailability.
• Material Science: A potential monomer or modifier for creating polymers with specific functional properties.
• Academic & R&D: Employed in university and industrial research laboratories for methodological development and exploring new chemical spaces.

Basic Information

Product Name	Morpholine-3,4-Dicarboxylic Acid 4-tert-Butyl Ester 3-Methyl Ester
CAS No.	212650-45-8
Molecular Formula	C12H19NO5
Molecular Weight	257.28 g/mol
Synonyms	3,4-Morpholinedicarboxylic acid, 4-(1,1-dimethylethyl) 3-methyl ester; 4-tert-Butyl 3-methyl morpholine-3,4-dicarboxylate; (3S,4R)-4-(tert-Butoxycarbonyl)-3-(methoxycarbonyl)morpholine; (3R,4S)-4-(tert-Butoxycarbonyl)-3-(methoxycarbonyl)morpholine; Morpholine-3,4-dicarboxylic acid 4-tert-butyl ester 3-methyl ester; BOC-Morpholine-3-COOMe; tert-Butyl methyl morpholine-3,4-dicarboxylate
EINECS	Contact for details

Quality Control

Our Morpholine-3,4-Dicarboxylic Acid 4-tert-Butyl Ester 3-Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for pharmaceutical R&D and production. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider inert gas purging to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	≥99.0% ee
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.