Description

2-Fluoro-6-Nitrobenzoic Acid Methyl Ester is a high-purity fluorinated aromatic building block essential for advanced organic synthesis. This compound matters as a versatile intermediate, enabling the precise introduction of fluorine and nitro functional groups into complex molecular architectures. It is primarily needed by R&D chemists and process development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of fluorinated drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the development of new-generation herbicides and pesticides, where the fluorine atom enhances biological activity and environmental stability.
• Material Science Research: Serves as a monomer or functionalizing agent in the creation of specialty polymers and liquid crystals with tailored electronic properties.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitution to construct complex, multi-substituted benzene derivatives.
• Dye and Pigment Intermediate: Facilitates the production of specialized nitro- and fluoro-substituted colorants with unique light-fastness and chromatic properties.

Basic Information

Product Name	2-Fluoro-6-Nitrobenzoic Acid Methyl Ester
CAS No.	212189-78-1
Molecular Formula	C8H6FNO4
Molecular Weight	199.14 g/mol
Synonyms	Methyl 2-Fluoro-6-nitrobenzoate; 2-Fluoro-6-nitrobenzoic acid methyl ester; Benzoic acid, 2-fluoro-6-nitro-, methyl ester; Methyl 2-fluoro-6-nitrobenzoate; 6-Nitro-2-fluorobenzoic acid methyl ester; 2-Fluoro-6-nitro methyl benzoate; Methyl (2-fluoro-6-nitrophenyl)formate
EINECS	Contact for details

Quality Control

Every batch of 2-Fluoro-6-Nitrobenzoic Acid Methyl Ester is produced and tested under a strict quality management system. We ensure compliance with relevant industry standards for fine chemical intermediates. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee batch-to-batch consistency and support your regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, the container should be amber-colored or stored in a dark environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.