Description

2-Fluoro-6-Nitrobenzoic Acid Methyl Ester is a versatile fluorinated aromatic ester building block, essential for advanced organic synthesis. Its molecular structure, featuring both a fluorine substituent and a nitro group, makes it a critical intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a fluorinated aromatic core.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides where the fluorine atom enhances biological activity and stability.
• Material Science Research: Serves as a monomer or functionalization agent in the creation of specialty polymers and advanced organic materials.
• Ligand and Catalyst Development: Employed in the preparation of complex ligands for catalysis and molecular recognition studies.
• Chemical Biology Probes: Utilized to synthesize fluorinated probes and tags for imaging and diagnostic applications.
• Academic and R&D Laboratories: A fundamental reagent for methodological development and exploratory synthesis in organic chemistry.

Basic Information

Product Name	2-Fluoro-6-Nitrobenzoic Acid Methyl Ester
CAS No.	212189-28-1
Molecular Formula	C8H6FNO4
Molecular Weight	199.14 g/mol
Synonyms	Methyl 2-fluoro-6-nitrobenzoate; 2-Fluoro-6-nitrobenzoic acid methyl ester; Benzoic acid, 2-fluoro-6-nitro-, methyl ester; Methyl 2-fluoro-6-nitrobenzenecarboxylate; 2-Fluoro-6-nitro methyl benzoate; 212189-28-1; Methyl o-fluoro-6-nitrobenzoate
EINECS	Contact for details

Quality Control

Our 2-Fluoro-6-Nitrobenzoic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.