Description

Dimethyl 2,2'-((2-((tert-Butoxycarbonyl)Amino)Ethyl)Azanediyl)Diacetate is a high-purity, protected amino acid derivative widely used as a critical building block in advanced organic synthesis. This compound is valued for its role in introducing a Boc-protected diamine moiety, enabling the controlled construction of complex molecular architectures. It is an essential intermediate for researchers and manufacturers in the pharmaceutical and biotechnology sectors, particularly in the development of peptide-based therapeutics, drug conjugates, and specialty polymers.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of peptide drugs, antibody-drug conjugates (ADCs), and other bioactive molecules requiring a protected diamine linker.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis to incorporate a functionalized, Boc-protected ethylenediamine unit into peptide chains.
• Bioconjugation Chemistry: Serves as a versatile linker for attaching payloads (e.g., cytotoxic drugs, fluorescent dyes, or polyethylene glycol (PEG)) to proteins, antibodies, or other biomolecules.
• Polymer Chemistry: Employed as a monomer or co-monomer for creating functionalized polymers with amine groups, useful in drug delivery systems and smart materials.
• Chemical Research & Development: A valuable reagent in medicinal chemistry for structure-activity relationship (SAR) studies and the exploration of new chemical entities.
• Protecting Group Strategy: The tert-butoxycarbonyl (Boc) group provides orthogonal protection for amines, facilitating multi-step synthetic sequences common in complex molecule assembly.

Basic Information

Product Name	Dimethyl 2,2'-((2-((tert-Butoxycarbonyl)Amino)Ethyl)Azanediyl)Diacetate
CAS No.	212143-39-0
Molecular Formula	C13H24N2O6
Molecular Weight	304.34 g/mol
Synonyms	Boc-N-amido-PEG2-acid methyl ester; 2,2'-(2-((tert-Butoxycarbonyl)amino)ethylazanediyl)diacetic acid dimethyl ester; Dimethyl 2,2'-(2-((tert-butoxycarbonyl)amino)ethylimino)diacetate; Boc-DADOO-dimethyl ester; N-Boc-ethylenediamine-N,N-diacetic acid dimethyl ester; tert-Butyl N-[2-[bis(2-methoxy-2-oxoethyl)amino]ethyl]carbamate
EINECS	Contact for details

Quality Control

Our Dimethyl 2,2'-((2-((tert-Butoxycarbonyl)Amino)Ethyl)Azanediyl)Diacetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our production adheres to cGMP guidelines where applicable, ensuring a reliable supply for research and pre-clinical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.