Description

Lonaprisan CAS NO 211254-73-8 is a high-purity, non-peptide progesterone receptor antagonist. This compound is of significant interest in pharmaceutical research and development, particularly for its targeted mechanism of action. It serves as a critical intermediate and active pharmaceutical ingredient (API) for researchers and manufacturers in the life sciences sector, enabling advancements in therapeutic areas such as oncology and reproductive health.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of advanced therapeutic agents.
• Progesterone Receptor Research: Used as a reference standard and tool compound in biochemical and pharmacological studies targeting progesterone receptors.
• Oncology Research: Investigated for its potential application in hormone-dependent cancers, such as breast and endometrial cancer.
• Reproductive Health R&D: Employed in the development of novel treatments for conditions like uterine fibroids and endometriosis.
• API Manufacturing: Utilized as an Active Pharmaceutical Ingredient in the production of finished dosage forms under cGMP guidelines.
• Preclinical Studies: Essential for in vitro and in vivo efficacy and safety profiling of new drug candidates.

Basic Information

Product Name	Lonaprisan
CAS No.	211254-73-8
Molecular Formula	C31H41N5O3
Molecular Weight	531.69 g/mol
Synonyms	ZK 230211; (8S,11R,13S,14S,17R)-11-[4-(Dimethylamino)phenyl]-17-hydroxy-13-methyl-17-prop-1-ynyl-1,2,6,7,8,11,12,14,15,16-decahydrocyclopenta[a]phenanthren-3-one; ZK-230211; Lonaprisanum; ZK230211
EINECS	Contact for details

Quality Control

Our Lonaprisan is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for pharmaceutical research and development. Certificates of Analysis (COA) with detailed HPLC, NMR, and MS data are provided to guarantee compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Water Content (KF)	≤1.0%
Residual Solvents (GC)	Complies with ICH Q3C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.