Description

(3-Aminomethyl-Phenoxy)-Acetic Acid tert-Butyl Ester is a high-purity, protected amino acid derivative that serves as a critical building block in advanced organic synthesis. This compound is valued for its bifunctional reactivity, featuring both a protected amine and a carboxylic acid ester group, enabling precise molecular construction. It is primarily utilized by research and development chemists and process scale-up teams in the pharmaceutical and agrochemical industries for the synthesis of complex active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in peptidomimetics and small molecule drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and plant growth regulators.
• Peptide Chemistry: Serves as a protected amino acid derivative for solid-phase and solution-phase peptide synthesis (SPPS).
• Ligand and Catalyst Development: Employed in the creation of novel chiral ligands, organocatalysts, and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Useful for synthesizing labeled compounds and molecular probes for biochemical and diagnostic research.
• Custom Synthesis & Contract Manufacturing: A versatile starting material for custom synthesis projects and scale-up manufacturing under cGMP conditions.

Basic Information

Product Name	(3-Aminomethyl-Phenoxy)-Acetic Acid tert-Butyl Ester
CAS No.	210115-55-2
Molecular Formula	C14H21NO3
Molecular Weight	251.32 g/mol
Synonyms	tert-Butyl (3-(aminomethyl)phenoxy)acetate; 2-[(3-Aminomethyl)phenoxy]acetic Acid 1,1-Dimethylethyl Ester; N-Boc-3-Aminomethylphenoxyacetic Acid tert-Butyl Ester (common misnomer); (3-(Aminomethyl)phenoxy)acetic Acid tert-Butyl Ester; Glycine, N-[(3-hydroxyphenyl)methyl]-, 1,1-dimethylethyl ester; tert-Butyl [(3-(aminomethyl)phenyl]oxy]acetate; (3-Aminobenzyloxy)acetic Acid tert-Butyl Ester
EINECS	Contact for details

Quality Control

Our (3-Aminomethyl-Phenoxy)-Acetic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specification results. Our quality commitment supports applications requiring high-purity intermediates for research and cGMP-compliant production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.