Description

Di-tert-Butyl 5-Bromopyridin-2-Ylimidodicarbonate is a high-purity, protected pyridine derivative primarily used as a sophisticated building block in advanced organic synthesis. This compound is critical for researchers and process chemists developing novel active pharmaceutical ingredients (APIs) and agrochemicals, where the bromine and protected imidodicarbonate functionalities offer precise sites for further chemical elaboration. Its primary value lies in enabling complex molecular construction with high selectivity and yield, making it essential for pharmaceutical R&D, agrochemical discovery, and specialty chemical manufacturing.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and fungicides, leveraging the pyridine core for bioactivity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the synthesis of organic electronic materials and photoactive compounds due to its bromine handle for cross-coupling reactions.
• Custom Chemical Synthesis: Provides a versatile scaffold for contract research organizations (CROs) and CDMOs to build custom molecules for client projects.
• Academic Research: Used in university and institutional labs for methodological studies in heterocyclic and organohalide chemistry.

Basic Information

Product Name	Di-tert-Butyl 5-Bromopyridin-2-Ylimidodicarbonate
CAS No.	209959-28-4
Molecular Formula	C14H19BrN2O4
Molecular Weight	359.22 g/mol
Synonyms	Di-tert-butyl (5-bromopyridin-2-yl)imidodicarbonate; 5-Bromo-2-pyridyl Di-tert-butyl Imidodicarbonate; 2,5-Di-tert-butoxycarbonylamino-5-bromopyridine (common name); 5-Bromo-2-pyridyl N,N-Bis(tert-butoxycarbonyl)amine; Di-Boc Protected 5-Bromo-2-aminopyridine; 2-Amino-5-bromopyridine Di-Boc Derivative; (5-Bromopyridin-2-yl)bis(tert-butoxycarbonyl)amine; DTBPBIC (abbreviation)
EINECS	Contact for details

Quality Control

Our Di-tert-Butyl 5-Bromopyridin-2-Ylimidodicarbonate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis, to ensure it meets the high standards required for research and scale-up applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container sealed to protect this light-sensitive material from moisture and atmospheric contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.