Description

6-Chloro-4-Methylpicolinonitrile is a versatile and high-value pyridine derivative, serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring both chloro and nitrile substituents, makes it an essential intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging its heterocyclic core.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in metal-catalyzed cross-coupling reactions.
• Material Science Research: Employed in the development of organic electronic materials and functional polymers due to its electron-deficient aromatic system.
• Custom Synthesis and Contract Manufacturing: A fundamental building block for custom synthesis projects requiring functionalized picolinonitrile scaffolds.

Basic Information

Product Name	6-Chloro-4-Methylpicolinonitrile
CAS No.	209858-74-2
Molecular Formula	C7H5ClN2
Molecular Weight	152.58 g/mol
Synonyms	6-Chloro-4-methylpyridine-2-carbonitrile; 4-Methyl-6-chloropicolinonitrile; 2-Cyano-6-chloro-4-methylpyridine; 6-Chloro-4-methyl-2-cyanopyridine; 6-Chloro-4-methyl-2-pyridinecarbonitrile; 2-Pyridinecarbonitrile, 6-chloro-4-methyl-; 6-Chloro-4-methylpicolinonitrile
EINECS	Contact for details

Quality Control

We maintain a rigorous quality management system to ensure batch-to-batch consistency and high purity. Our products undergo comprehensive analytical testing, including HPLC, GC, and NMR, to verify identity and purity against stringent internal specifications. A Certificate of Analysis (COA) is provided with each shipment, detailing all relevant quality parameters. We support cGMP-compliant manufacturing for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.