Description

Bzl-Ile-Ome Hcl is a protected amino acid derivative, specifically the hydrochloride salt of benzyl-L-isoleucine methyl ester. This compound serves as a crucial building block in organic synthesis, particularly in the production of complex peptides and pharmaceutical intermediates. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors who require high-purity chiral starting materials.

Application

• Peptide Synthesis: As a key intermediate for the solid-phase and solution-phase synthesis of bioactive peptides.
• Pharmaceutical Research: Used in the development and scale-up of active pharmaceutical ingredients (APIs) and prodrugs.
• Bioconjugation: Acts as a linker or spacer molecule in the design of antibody-drug conjugates (ADCs) and other bioconjugates.
• Chemical Biology: Employed in the study of enzyme mechanisms and protein-protein interactions as a substrate or inhibitor analog.
• Protecting Group Chemistry: Utilized in multi-step organic syntheses where selective protection of the amino and carboxyl groups is required.
• Reference Standard: Serves as a high-purity analytical standard for quality control in GMP manufacturing environments.

Basic Information

Product Name	Bzl-Ile-Ome Hcl
CAS No.	209325-69-9
Molecular Formula	C15H22ClNO3
Molecular Weight	299.79 g/mol
Synonyms	Benzyloxycarbonyl-L-isoleucine methyl ester hydrochloride; Z-Ile-OMe·HCl; N-Cbz-L-isoleucine methyl ester hydrochloride; Nα-Carbobenzoxy-L-isoleucine methyl ester hydrochloride; (2S,3S)-2-[[(Benzyloxy)carbonyl]amino]-3-methylpentanoic acid methyl ester hydrochloride; Cbz-Ile-OMe HCl; N-Benzyloxycarbonyl-L-isoleucine methyl ester hydrochloride
EINECS	Contact for details

Quality Control

Our Bzl-Ile-Ome Hcl is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation to ensure it meets the stringent requirements for pharmaceutical research and GMP applications. Certificates of Analysis (COA) with full traceability are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.