Description

2-Iodo-Pyridin-3-Ylamine is a halogenated pyridine derivative of significant interest in advanced organic synthesis. This compound serves as a versatile and valuable building block for constructing complex nitrogen-containing heterocycles, which are core structures in many active pharmaceutical ingredients. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and material science industries for the development of new molecules and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides with specific modes of action.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for transition metal catalysis and organocatalysts.
• Material Science Research: Acts as a monomer or functionalizing agent in the creation of advanced polymers and organic electronic materials.
• Chemical Biology Probes: Utilized to create tagged molecules for studying biological pathways and protein interactions.
• Cross-Coupling Reactions: Serves as a crucial substrate in palladium-catalyzed cross-coupling reactions, such as Suzuki and Buchwald-Hartwig aminations.

Basic Information

Product Name	2-Iodo-Pyridin-3-Ylamine
CAS No.	209286-97-5
Molecular Formula	C5H5IN2
Molecular Weight	220.01 g/mol
Synonyms	3-Amino-2-iodopyridine; 2-Iodo-3-pyridinamine; 2-Iodopyridin-3-amine; 3-Pyridinamine, 2-iodo-; 2-Iodo-3-aminopyridine; 2-Iodo-3-pyridylamine; 3-Amino-2-iodo-pyridine
EINECS	Contact for details

Quality Control

Our 2-Iodo-Pyridin-3-Ylamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.