Description

2-Iodo-3-Nitropyridine is a versatile halogenated and nitrated heterocyclic building block of significant importance in advanced organic synthesis. Its unique structure, featuring both an iodine and a nitro group on the pyridine ring, makes it a critical intermediate for constructing complex molecules. This compound is primarily sought after by researchers and process chemists in the pharmaceutical, agrochemical, and material science industries for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in the development of kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the pyridine core is a common structural motif.
• Material Science Research: Serves as a building block for creating organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components for organic light-emitting diodes (OLEDs).
• Cross-Coupling Reactions: The iodine atom is an excellent handle for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira), enabling the introduction of diverse functional groups.
• Nucleophilic Aromatic Substitution: The nitro group activates the ring for substitution reactions, allowing for further functionalization of the pyridine scaffold.
• Chemical Biology & Proteomics: Can be utilized as a reagent for bioconjugation or as a tag in the development of chemical probes.

Basic Information

Product Name	2-Iodo-3-Nitropyridine
CAS No.	209286-96-4
Molecular Formula	C5H3IN2O2
Molecular Weight	249.99 g/mol
Synonyms	3-Nitro-2-iodopyridine; 2-Iodo-3-nitropyridine; Pyridine, 2-iodo-3-nitro-; 3-Nitro-2-iodopyridine; Iodonitropyridine
EINECS	Contact for details

Quality Control

Our 2-Iodo-3-Nitropyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials and sources of ignition.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.