Description

2-(Bromomethyl)-4-Chlorothieno[3,2-C]Pyridine is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its molecular architecture, featuring both bromomethyl and chloro substituents on a fused thienopyridine core, makes it a versatile precursor for constructing complex molecular frameworks. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of potential drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors and other biologically active heterocycles.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its halogenated structure for further functionalization.
• Material Science Precursor: Serves as a building block for creating novel organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components for organic semiconductors.
• Cross-Coupling Reactions: The bromomethyl group is an excellent handle for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck), enabling rapid diversification of the molecular structure.
• Nucleophilic Substitution: The reactive halogen sites allow for facile nucleophilic substitution, facilitating the introduction of amines, alkoxides, and other functional groups.

Basic Information

Product Name	2-(Bromomethyl)-4-Chlorothieno[3,2-C]Pyridine
CAS No.	209286-63-5
Molecular Formula	C9H5BrClNS
Molecular Weight	278.57 g/mol
Synonyms	4-Chloro-2-(bromomethyl)thieno[3,2-c]pyridine; 2-Bromomethyl-4-chlorothieno[3,2-c]pyridine; 4-Chloro-2-(bromomethyl)-thieno[3,2-c]pyridine; Thieno[3,2-c]pyridine, 2-(bromomethyl)-4-chloro-; 209286-63-5; 4-Chloro-2-bromomethylthieno[3,2-c]pyridine
EINECS	Contact for details

Quality Control

Every batch of 2-(Bromomethyl)-4-Chlorothieno[3,2-C]Pyridine is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and development. A Certificate of Analysis (COA) detailing purity (typically ≥95% by HPLC), identity confirmation (by NMR and IR), and impurity profile is supplied with each shipment to guarantee traceability and consistency for your critical synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.