Description

(+/-)-1-(4-Bromophenyl)Ethyl Isocyanate is a versatile chiral building block featuring a reactive isocyanate group and a brominated aromatic ring. This bifunctional nature makes it a critical intermediate for synthesizing complex molecules with tailored properties. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and advanced material science.

Application

• Pharmaceutical Intermediate: Key precursor for the synthesis of urea and carbamate derivatives, which are common scaffolds in active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the bromophenyl moiety for bioactivity.
• Polymer Modification: Serves as a cross-linking or chain-extending agent in polyurethane and specialty polymer formulations to enhance material properties.
• Chemical Biology Probes: Utilized to create isocyanate-labeled compounds for studying enzyme inhibition or protein interactions.
• Ligand and Catalyst Development: Acts as a starting material for synthesizing chiral ligands used in asymmetric catalysis.
• Custom Synthesis & Contract Manufacturing: A valuable reagent for custom synthesis houses serving the fine chemical and life science sectors.

Basic Information

Product Name	(+/-)-1-(4-Bromophenyl)Ethyl Isocyanate
CAS No.	207974-15-0
Molecular Formula	C9H8BrNO
Molecular Weight	226.07 g/mol
Synonyms	1-(4-Bromophenyl)ethyl isocyanate; α-Methyl-4-bromobenzyl isocyanate; 4-Bromo-α-methylbenzyl isocyanate; (±)-1-(4-Bromophenyl)ethyl isocyanate; rac-1-(4-Bromophenyl)ethyl isocyanate; 1-(4-Bromophenyl)ethan-1-yl isocyanate; (RS)-1-(4-Bromophenyl)ethyl isocyanate
EINECS	Contact for details

Quality Control

Our (+/-)-1-(4-Bromophenyl)Ethyl Isocyanate is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation and polymerization.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.