Description

(9H-Fluoren-9-Yl)Methyl Piperidine-1-Carboxylate CAS NO 207558-19-8 is a specialized organic compound belonging to the class of fluorenylmethyloxycarbonyl (Fmoc) protected amines. This chemical serves as a crucial building block and protecting group reagent in sophisticated organic synthesis. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and biotechnology sectors. The compound enables the controlled synthesis of complex molecules, including peptides and active pharmaceutical ingredients (APIs).

Application

• Solid-Phase Peptide Synthesis (SPPS): As an Fmoc-protected piperidine derivative, it is a key reagent for introducing the piperidine moiety during the stepwise assembly of peptides, protecting the amine group from unwanted reactions.
• Pharmaceutical Intermediate: Acts as a critical synthetic precursor in the development of novel drug candidates, particularly those targeting neurological disorders, where the piperidine scaffold is a common pharmacophore.
• Combinatorial Chemistry: Used in the generation of diverse chemical libraries for high-throughput screening in drug discovery programs to identify new lead compounds.
• Bioconjugation: Employed in the synthesis of linker molecules and probes for bioconjugation techniques, useful in developing antibody-drug conjugates (ADCs) or diagnostic agents.
• Organic Synthesis Research: Serves as a versatile building block for academic and industrial research focused on developing new synthetic methodologies and complex natural product analogs.

Basic Information

Product Name	(9H-Fluoren-9-Yl)Methyl Piperidine-1-Carboxylate
CAS No.	207558-19-8
Molecular Formula	C21H21NO2
Molecular Weight	319.40 g/mol
Synonyms	1-Fmoc-piperidine; Fmoc-Piperidine; N-Fmoc-piperidine; N-(9-Fluorenylmethoxycarbonyl)piperidine; 1-[(9H-Fluoren-9-ylmethoxy)carbonyl]piperidine; Piperidine-1-carboxylic acid 9H-fluoren-9-ylmethyl ester; 1-(9-Fluorenylmethyloxycarbonyl)piperidine
EINECS	Contact for details

Quality Control

Our (9H-Fluoren-9-Yl)Methyl Piperidine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment supports applications in cGMP and ISO-certified research and development environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.