Description

3-Bromo-2-Fluorobenzoic Acid Methyl Ester is a high-purity fluorinated and brominated aromatic building block essential for advanced organic synthesis. This compound matters because it provides a versatile scaffold for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel compounds with specific biological or physical properties.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of drug candidates, especially those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the fluorine and bromine atoms for enhanced bioactivity and environmental stability.
• Liquid Crystal & OLED Material Precursor: Serves as a building block for fluorinated aromatic components in advanced electronic display materials.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl structures.
• Functional Group Transformation: The ester group can be hydrolyzed to the corresponding acid or reduced to the alcohol, enabling diverse downstream chemical modifications.
• Chemical Reference Standard: Used as an analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	3-Bromo-2-Fluorobenzoic Acid Methyl Ester
CAS No.	206551-41-9
Molecular Formula	C8H6BrFO2
Molecular Weight	233.04 g/mol
Synonyms	Methyl 3-bromo-2-fluorobenzoate; 2-Fluoro-3-bromobenzoic acid methyl ester; Benzoic acid, 3-bromo-2-fluoro-, methyl ester; 3-Bromo-2-fluorobenzoic acid methyl ester; Methyl 2-fluoro-3-bromobenzoate
EINECS	Contact for details

Quality Control

Our 3-Bromo-2-Fluorobenzoic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical characteristics is provided with every shipment to guarantee supply consistency and traceability for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Melting Point	Contact for details
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.