Description

Cyclobutanecarboxylic Acid, 3-(Cyanomethylene)-, Methyl Ester (9Ci) is a specialized organic building block featuring a cyclobutane ring fused with a cyano-substituted methylene ester group. This compound is valued for its unique strained-ring structure and functional group versatility, making it a critical intermediate in advanced synthetic chemistry. It is primarily sought by research and development teams in the pharmaceutical and agrochemical sectors for constructing novel molecular scaffolds and active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or requiring complex, strained-ring pharmacophores.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or insecticides where the cyclobutane core can impart specific biological activity and metabolic stability.
• Material Science Chemistry: Acts as a monomer or cross-linking agent in the research of advanced polymers with tailored thermal or mechanical properties.
• Organic Synthesis Building Block: Employed in academic and industrial R&D for cycloaddition reactions, ring-opening transformations, and the construction of complex natural product analogs.
• Ligand and Catalyst Development: Utilized in the preparation of novel chiral ligands or organocatalysts for asymmetric synthesis applications.

Basic Information

Item	Details
Product Name	Cyclobutanecarboxylic Acid, 3-(Cyanomethylene)-, Methyl Ester (9Ci)
CAS No.	206445-57-0
Molecular Formula	C8H9NO2
Molecular Weight	151.16 g/mol
Synonyms	Methyl 3-(cyanomethylene)cyclobutanecarboxylate; 3-(Cyanomethylene)cyclobutanecarboxylic Acid Methyl Ester; Cyclobutanecarboxylic acid, 3-(cyanomethylene)-, methyl ester; Methyl 3-(cyanomethylidene)cyclobutanecarboxylate; 206445-57-0; 3-Cyanomethylene-cyclobutanecarboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our production of Cyclobutanecarboxylic Acid, 3-(Cyanomethylene)-, Methyl Ester adheres to stringent internal quality protocols to ensure batch-to-batch consistency and high purity. Each lot is characterized using advanced analytical techniques including NMR, HPLC, and GC-MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, prolonged exposure to direct light should be avoided.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0% (Standard Grade)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.