Description

D-Threo-Pentonic Acid, 2,3-Anhydro-4,5-Dideoxy-4,4-Dimethyl-, Methyl Ester is a specialized chiral building block and synthetic intermediate of significant interest in advanced organic synthesis. Its unique anhydro-dideoxy structure with a methyl ester functional group makes it a valuable precursor for constructing complex molecules with defined stereochemistry. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), nucleoside analogs, and other fine chemicals where precise stereocontrol is critical.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and development of novel therapeutic agents, including antiviral and anticancer compounds.
• Nucleoside Analog Synthesis: Serves as a sophisticated precursor in the synthesis of modified nucleosides and nucleotides for medicinal chemistry applications.
• Asymmetric Synthesis: Used as a building block in stereoselective reactions to introduce complex, multi-functionalized chiral centers into target molecules.
• Chemical Biology Research: Employed in the design and synthesis of molecular probes, enzyme inhibitors, and other biologically active tools.
• Process Chemistry Development: Investigated for scalable routes in the production of high-value fine chemicals and advanced intermediates under GMP conditions.
• Academic & Industrial R&D: A critical reagent for methodological studies in organic chemistry and for exploring new synthetic pathways.

Basic Information

Product Name	D-Threo-Pentonic Acid, 2,3-Anhydro-4,5-Dideoxy-4,4-Dimethyl-, Methyl Ester
CAS No.	206365-78-8
Molecular Formula	C8H14O4
Molecular Weight	174.19 g/mol
Synonyms	Methyl 2,3-anhydro-4,5-dideoxy-4,4-dimethyl-D-threo-pentonate; (2R,3S)-2,3-Anhydro-4,5-dideoxy-4,4-dimethyl-D-threonic acid methyl ester; Methyl (2R,3S)-2,3-anhydro-4,5-dideoxy-4,4-dimethyl-D-threonate; D-Threo-Pentonic acid, 2,3-anhydro-4,5-dideoxy-4,4-dimethyl-, methyl ester; Anhydro-dideoxy-dimethyl-threonate methyl ester; CAS 206365-78-8
EINECS	Contact for details

Quality Control

Our production of D-Threo-Pentonic Acid, 2,3-Anhydro-4,5-Dideoxy-4,4-Dimethyl-, Methyl Ester adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing critical parameters such as chiral purity, chemical purity (by HPLC), and identification. We support cGMP compliance for advanced intermediates and can tailor specifications to meet specific research or development project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed under an inert atmosphere if necessary to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.