Description

1-(Triisopropylsilyloxy)Cyclopropylcarboxylic Acid Methyl Ester is a high-value organosilicon-protected cyclopropane derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its primary value lies in the triisopropylsilyl (TIPS) protecting group, which offers exceptional stability under a wide range of reaction conditions while being selectively removable. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require precise control over molecular architecture during multi-step syntheses.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of complex drug candidates, particularly those containing strained cyclopropane rings, which are prevalent in bioactive molecules.
• Agrochemical Synthesis: Used in the development of novel pesticides and herbicides where the cyclopropane moiety imparts specific biological activity and stability.
• Material Science Precursor: Serves as a monomer or functionalization agent in the creation of specialty polymers and advanced organic materials with tailored properties.
• Organic Synthesis Reagent: Employed in cross-coupling reactions, ring-opening transformations, and as a protected carboxylic acid equivalent in complex molecule assembly.
• Asymmetric Catalysis Substrate: Utilized in the development and study of chiral catalysts and methodologies due to its prochiral and sterically defined structure.
• Chemical Biology Probe Development: Acts as a scaffold for creating molecular probes to study enzyme function and biological pathways.

Basic Information

Item	Detail
Product Name	1-(Triisopropylsilyloxy)Cyclopropylcarboxylic Acid Methyl Ester
CAS No.	205756-59-8
Molecular Formula	C15H30O3Si
Molecular Weight	286.49 g/mol
Synonyms	Methyl 1-(triisopropylsilyloxy)cyclopropanecarboxylate; 1-(Triisopropylsilyloxy)cyclopropanecarboxylic Acid Methyl Ester; Cyclopropanecarboxylic acid, 1-[(triisopropylsilyl)oxy]-, methyl ester; Methyl 1-((triisopropylsilyl)oxy)cyclopropanecarboxylate; TIPS-protected cyclopropane ester; Methyl 1-(TIPS-oxy)cyclopropanecarboxylate; 205756-59-8
EINECS	Contact for details

Quality Control

Every batch of 1-(Triisopropylsilyloxy)Cyclopropylcarboxylic Acid Methyl Ester is manufactured under strict quality management systems. We employ advanced analytical techniques, including HPLC, GC, and NMR, to ensure identity, purity, and consistency meet the exacting standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to guarantee traceability and support your regulatory and R&D documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.