Description

Ethyl 2-Fluoro-4-Iodobenzoate is a high-purity fluorinated and iodinated aromatic ester building block of significant importance in modern synthetic chemistry. Its unique halogenated structure makes it a versatile intermediate for constructing complex molecules, particularly in pharmaceutical and agrochemical research. This compound is primarily sought after by R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), liquid crystal materials, and advanced organic electronic compounds.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Research: Used in the development of new-generation herbicides and pesticides with enhanced efficacy and selectivity.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorinated liquid crystal molecules and organic light-emitting diode (OLED) materials, where halogen atoms fine-tune electronic properties.
• Cross-Coupling Reactions: The iodine moiety makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to create biaryl and other complex structures.
• Chemical Biology & Proteomics: Utilized as a tagging or labeling reagent due to the reactivity of the iodine atom for bioconjugation strategies.
• Advanced Material Science: Employed in the synthesis of monomers for specialty polymers with specific optical or thermal properties.

Basic Information

Product Name	Ethyl 2-Fluoro-4-Iodobenzoate
CAS No.	205750-82-9
Molecular Formula	C9H8FIO2
Molecular Weight	294.06 g/mol
Synonyms	Benzoic acid, 2-fluoro-4-iodo-, ethyl ester; 2-Fluoro-4-iodobenzoic acid ethyl ester; Ethyl 2-fluoro-4-iodobenzoate; Ethyl 4-iodo-2-fluorobenzoate; 205750-82-9; Ethyl 2-fluoro-4-iodobenzoate CAS NO 205750-82-9; 4-Iodo-2-fluorobenzoic Acid Ethyl Ester
EINECS	Contact for details

Quality Control

Our Ethyl 2-Fluoro-4-Iodobenzoate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical parameters. Our quality commitment aligns with cGMP principles for advanced intermediates, ensuring reliability for your most demanding research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.