Description

2-Phenylsulphonylpyridine-5-Carbonitrile is a high-purity, specialized organic intermediate featuring a sulfone and nitrile functional group on a pyridine scaffold. This compound matters for its role as a critical building block in the synthesis of advanced pharmaceutical agents and agrochemicals, enabling the introduction of key pharmacophores. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly for kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, leveraging its heterocyclic structure for bioactivity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in catalytic processes and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of organic electronic materials and photoactive compounds due to its electron-withdrawing sulfone and nitrile groups.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke chemical production and scale-up projects.

Basic Information

Product Name	2-Phenylsulphonylpyridine-5-Carbonitrile
CAS No.	205514-29-0
Molecular Formula	C₁₂H₈N₂O₂S
Molecular Weight	244.27 g/mol
Synonyms	5-Cyano-2-(phenylsulfonyl)pyridine; 2-(Phenylsulfonyl)pyridine-5-carbonitrile; 2-(Benzenesulfonyl)pyridine-5-carbonitrile; Pyridine, 5-cyano-2-(phenylsulfonyl)-; 205514-29-0; 2-Phenylsulfonyl-5-cyanopyridine; 5-Cyano-2-phenylsulfonylpyridine
EINECS	Contact for details

Quality Control

Our 2-Phenylsulphonylpyridine-5-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.