Description

Ethyl (R)-2-Hydroxy-2-Methylbenzenepropanoate is a high-purity chiral intermediate characterized by its specific stereochemistry at the hydroxy-bearing carbon. This compound is valued for its role in the synthesis of enantiomerically pure pharmaceuticals and fine chemicals, where optical purity is critical for efficacy and regulatory approval. It is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and advanced material sectors for developing new active ingredients and specialty products.

Application

• Key chiral building block in the asymmetric synthesis of pharmaceutical active ingredients.
• Intermediate for the production of agrochemicals, such as herbicides and fungicides with specific stereochemical requirements.
• Starting material in academic and industrial research for developing novel ligands and catalysts.
• Precursor in the synthesis of fine chemicals and specialty materials where the (R)-enantiomer configuration is essential.
• Used in process development and scale-up activities for new chemical entities (NCEs).

Basic Information

Product Name	Ethyl (R)-2-Hydroxy-2-Methylbenzenepropanoate
CAS No.	205505-45-9
Molecular Formula	C12H16O3
Molecular Weight	208.25 g/mol
Synonyms	(R)-Ethyl 2-Hydroxy-2-methyl-3-phenylpropanoate; (R)-2-Hydroxy-2-methyl-3-phenylpropionic acid ethyl ester; Benzenepropanoic acid, 2-hydroxy-2-methyl-, ethyl ester, (R)-; Ethyl (R)-2-hydroxy-2-methyl-3-phenylpropionate; (R)-α-Hydroxy-α-methylhydrocinnamic acid ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl (R)-2-Hydroxy-2-Methylbenzenepropanoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for synthetic intermediates. Certificates of Analysis (COA) detailing identity, purity, and enantiomeric excess are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong acids and organic solvents. The container must be kept tightly closed in a dry environment.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.