Description

Neopentyl 4-(Trifluoromethyl)Benzoate is a specialized organic ester compound featuring a neopentyl alcohol backbone and a trifluoromethyl-substituted benzoate group. This structure offers a unique combination of steric hindrance and fluorinated properties, making it a valuable intermediate for advanced material synthesis. It is primarily sought by R&D chemists and process engineers in the pharmaceutical and agrochemical sectors for developing novel active ingredients and performance chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring fluorinated motifs for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group can improve pesticidal activity and environmental profile.
• Liquid Crystal & OLED Materials: Acts as a precursor or modifying agent in the development of fluorinated liquid crystals and organic light-emitting diode (OLED) materials, contributing to improved electronic properties and thermal stability.
• Polymer & Resin Modifier: Employed to introduce fluorinated and bulky neopentyl groups into polymer chains, enhancing properties like chemical resistance, weatherability, and lowering dielectric constant in specialty coatings and resins.
• Organic Synthesis Reagent: Functions as a protected or activated ester form in complex multi-step organic syntheses, including peptide coupling and cross-coupling reactions.

Basic Information

Product Name	Neopentyl 4-(Trifluoromethyl)Benzoate
CAS No.	204779-82-8
Molecular Formula	C13H15F3O2
Molecular Weight	260.25 g/mol
Synonyms	4-(Trifluoromethyl)benzoic acid neopentyl ester; Neopentyl p-trifluoromethylbenzoate; 2,2-Dimethylpropyl 4-(trifluoromethyl)benzoate; Benzoic acid, 4-(trifluoromethyl)-, 2,2-dimethylpropyl ester; 2,2-Dimethylpropyl α,α,α-trifluoro-p-toluate; Neopentyl alcohol, 4-trifluoromethylbenzoate
EINECS	Contact for details

Quality Control

Our Neopentyl 4-(Trifluoromethyl)Benzoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong acids and incompatible materials such as strong oxidizing agents. The container should be kept tightly sealed when not in use to minimize exposure to moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.