Description

Alanine, n-Acetyl-3-Cyano-, Methyl Ester (9Ci) is a high-purity, non-natural amino acid derivative characterized by its cyano and acetyl-protected functional groups. This specialized building block is critical for advanced organic synthesis, particularly in the development of novel pharmaceuticals and bioactive compounds. It is primarily utilized by research institutions and industrial R&D departments focused on medicinal chemistry, peptide mimetics, and the synthesis of complex heterocycles.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), especially for protease inhibitors and other targeted therapies.
• Peptidomimetics Research: Used to construct modified peptide backbones, enabling the study of structure-activity relationships and the enhancement of metabolic stability in peptide-based drug candidates.
• Agrochemical Synthesis: Acts as a precursor in the synthesis of novel herbicides and plant growth regulators that require specific chiral centers for biological activity.
• Chemical Biology Probes: Employed in the design and synthesis of activity-based probes (ABPs) and other tools for studying enzyme function and mechanism.
• Material Science: Investigated as a monomer or cross-linking agent for creating functionalized polymers with specific chemical handles for further modification.

Basic Information

Product Name	Alanine, n-Acetyl-3-Cyano-, Methyl Ester (9Ci)
CAS No.	204767-38-4
Molecular Formula	C7H10N2O3
Molecular Weight	170.17 g/mol
Synonyms	Methyl 2-acetamido-3-cyanopropanoate; Methyl N-acetyl-3-cyanoalaninate; 2-Acetamido-3-cyano-propionic acid methyl ester; N-Acetyl-3-cyanoalanine methyl ester; (2R)-2-Acetamido-3-cyanopropanoic acid methyl ester (for enantiomer); Alanine, N-acetyl-3-cyano-, methyl ester; AC-CN-Ala-OMe
EINECS	Contact for details

Quality Control

Our Alanine, n-Acetyl-3-Cyano-, Methyl Ester (9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assessment, to ensure it meets the exacting standards required for research and development applications. A detailed Certificate of Analysis (COA) providing HPLC purity, chiral purity, and identity confirmation is supplied with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere for long-term storage to maintain optimal purity and stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (specify enantiomer)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.