Description

Ethyl 3-(tert-Butoxycarbonylamino)-2,2-Dimethylpropanoate is a high-purity, protected amino acid ester derivative that serves as a critical building block in advanced organic synthesis. Its primary value lies in providing a versatile and reactive handle for the controlled introduction of a sterically hindered, Boc-protected amino acid moiety into complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the development of novel active ingredients, peptide mimetics, and specialty fine chemicals.

Application

• Pharmaceutical Intermediates: A key synthon in the synthesis of complex drug candidates, especially those requiring sterically hindered amino acid components.
• Peptidomimetics & PROTACs: Used in constructing peptide-like molecules and Proteolysis Targeting Chimeras (PROTACs) for targeted protein degradation.
• Agrochemical Synthesis: Serves as a building block for creating novel herbicides, fungicides, and plant growth regulators with specific chiral centers.
• Custom Synthesis & Contract Manufacturing: Employed by CDMOs for the custom production of complex, high-value organic molecules for clients.
• Academic & R&D Laboratories: A valuable reagent for methodological development in organic chemistry and medicinal chemistry research programs.
• Specialty Polymer Modifiers: Can be used to introduce functional amino groups into polymer backbones for specialized material properties.

Basic Information

Product Name	Ethyl 3-(tert-Butoxycarbonylamino)-2,2-Dimethylpropanoate
CAS No.	204514-14-7
Molecular Formula	C₁₂H₂₃NO₄
Molecular Weight	245.32 g/mol
Synonyms	Ethyl 3-[(tert-Butoxycarbonyl)amino]-2,2-dimethylpropanoate; 3-[(tert-Butoxycarbonyl)amino]-2,2-dimethylpropanoic Acid Ethyl Ester; 2,2-Dimethyl-3-[(2-methylpropan-2-yl)oxycarbonylamino]propanoic Acid Ethyl Ester; Boc-β-aminoisobutyric Acid Ethyl Ester; Boc-Aib-OEt; Boc-3-Amino-2,2-dimethylpropionic Acid Ethyl Ester; N-Boc-3-Amino-2,2-dimethylpropionic Acid Ethyl Ester
EINECS	Contact for details

Quality Control

Our Ethyl 3-(tert-Butoxycarbonylamino)-2,2-Dimethylpropanoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all relevant specifications. Our production adheres to cGMP principles where applicable, ensuring reliable batch-to-batch consistency for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if possible to maximize shelf-life stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.