Description

2,8-Diaza-Spiro[4.5]Decane-3,8-Dicarboxylic Acid 8-tert-Butyl Ester 3-Ethyl Ester is a high-value, multifunctional spirocyclic building block and intermediate in advanced organic synthesis. Its unique constrained spirocyclic structure and dual ester-protected carboxylic acid groups make it a critical component for constructing complex molecular architectures with precise stereochemistry. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of novel active ingredients, heterocyclic compounds, and chiral ligands.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of spirocyclic drug candidates targeting CNS disorders, metabolic diseases, and infectious diseases.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides with spirocyclic core structures for enhanced efficacy and selectivity.
• Chiral Ligand & Catalyst Precursor: Serves as a precursor for sophisticated chiral ligands and organocatalysts used in asymmetric synthesis.
• Chemical Biology & Proteomics: Employed as a scaffold or linker in the design of molecular probes, activity-based probes (ABPs), and protein conjugation reagents.
• Material Science Research: Investigated as a monomer or cross-linker for creating novel polymers with specific thermal or mechanical properties derived from its rigid spirocyclic geometry.
• Academic & Contract Research: A valuable reagent for methodological development in organic chemistry, particularly in studies involving ring transformations and multicomponent reactions.

Basic Information

Item	Details
Product Name	2,8-Diaza-Spiro[4.5]Decane-3,8-Dicarboxylic Acid 8-tert-Butyl Ester 3-Ethyl Ester
CAS No.	203934-60-5
Molecular Formula	C16H28N2O4
Molecular Weight	312.41 g/mol
Synonyms	8-tert-Butyl 3-ethyl 2,8-diazaspiro[4.5]decane-3,8-dicarboxylate; 2,8-Diazaspiro[4.5]decane-3,8-dicarboxylic acid, 8-(1,1-dimethylethyl) 3-ethyl ester; Ethyl 8-(tert-butoxycarbonyl)-2,8-diazaspiro[4.5]decane-3-carboxylate; 3-Ethyl 8-tert-butyl 2,8-diazaspiro[4.5]decane-3,8-dicarboxylate; BOC-Spirocyclic Diamine Ester; tert-Butyl ethyl 2,8-diazaspiro[4.5]decane-3,8-dicarboxylate; Spirocyclic Diamine Derivative
EINECS	Contact for details

Quality Control

Our 2,8-Diaza-Spiro[4.5]Decane-3,8-Dicarboxylic Acid 8-tert-Butyl Ester 3-Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural identity. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment to support your R&D and quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.