Description

tert-Butyl 2-Oxo-7-Azaspiro[3.5]Nonane-7-Carboxylate is a high-value, protected heterocyclic building block used in advanced organic synthesis. This compound is a critical intermediate for constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs). It is essential for medicinal chemistry researchers and process development chemists in the pharmaceutical and agrochemical industries seeking to create new bioactive molecules with spirocyclic motifs.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of drug candidates featuring the 7-azaspiro[3.5]nonane scaffold, which is of high interest in medicinal chemistry.
• Protease Inhibitor Research: Used in the development of inhibitors for various enzymes, including kinases and proteases, due to its constrained, three-dimensional structure.
• Agrochemical Synthesis: Serves as a building block for novel herbicides, fungicides, and insecticides that require specific spirocyclic frameworks for bioactivity.
• Chemical Biology Probes: Employed in the creation of molecular probes and tool compounds for studying biological pathways and target validation.
• Peptidomimetics: The structure is valuable for designing peptide mimics that enhance metabolic stability and bioavailability.
• Material Science Research: Potential precursor for specialty polymers or ligands in catalysis due to its rigid, nitrogen-containing bicyclic system.

Basic Information

Product Name	tert-Butyl 2-Oxo-7-Azaspiro[3.5]Nonane-7-Carboxylate
CAS No.	203661-69-2
Molecular Formula	C13H21NO3
Molecular Weight	239.31 g/mol
Synonyms	7-Boc-2-oxo-7-azaspiro[3.5]nonane; tert-Butyl 2-oxo-7-azaspiro[3.5]nonane-7-carboxylate; 2-Oxo-7-azaspiro[3.5]nonane-7-carboxylic acid tert-butyl ester; 7-(tert-Butoxycarbonyl)-7-azaspiro[3.5]nonan-2-one; Boc-7-azaspiro[3.5]nonan-2-one; 203661-69-2; Azaspiro compound Boc-protected
EINECS	Contact for details

Quality Control

Our tert-Butyl 2-Oxo-7-Azaspiro[3.5]Nonane-7-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing purity, impurities, and physical characteristics are provided with every shipment to support your R&D and cGMP-compliant processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is sensitive to strong acids and organic solvents; keep away from incompatible materials. For long-term storage under an inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.