Description

4-Chloro-3-Fluorobenzoic Acid Ethyl Ester is a high-purity fluorinated benzoate derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its bifunctional halogenated structure, which enables precise molecular modifications for creating complex target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active ingredients and novel intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of active pharmaceutical ingredients (APIs), especially those containing fluorinated aromatic systems.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides where the chloro-fluoro substitution pattern is beneficial.
• Liquid Crystal Material Precursor: Serves as a starting material for the synthesis of fluorinated liquid crystal compounds used in display technologies.
• Organic Electronics: Employed in the development of organic semiconductors and charge-transport materials due to its aromatic and halogenated structure.
• Cross-Coupling Reactions: Acts as a substrate in palladium-catalyzed reactions like Suzuki or Stille couplings for constructing biaryl systems.
• Chemical Research & Development: A versatile reagent for exploring new synthetic methodologies and creating specialized chemical libraries.

Basic Information

Product Name	4-Chloro-3-Fluorobenzoic Acid Ethyl Ester
CAS No.	203573-08-4
Molecular Formula	C9H8ClFO2
Molecular Weight	202.61 g/mol
Synonyms	Ethyl 4-Chloro-3-fluorobenzoate; Benzoic acid, 4-chloro-3-fluoro-, ethyl ester; 4-Chloro-3-fluorobenzoic acid ethyl ester; 3-Fluoro-4-chlorobenzoic acid ethyl ester; Ethyl 3-fluoro-4-chlorobenzoate; 203573-08-4; 4-Chloro-3-fluorobenzoic acid, ethyl ester
EINECS	Contact for details

Quality Control

Our 4-Chloro-3-Fluorobenzoic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specified parameters. Our quality commitment ensures the material meets the stringent requirements for research and commercial synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.