Description

Cyclohexanecarboxylic Acid, 1-Amino-4-Ethoxy-, Methyl Ester, cis- (9Ci) is a specialized chiral intermediate featuring a cis-configured cyclohexane ring with amino and ethoxy substituents. This compound matters for its role as a key building block in the synthesis of complex, high-value molecules, particularly in the pharmaceutical sector where stereochemical purity is critical. It is needed by research chemists and process development teams in pharmaceutical, agrochemical, and advanced material industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), especially those targeting central nervous system or cardiovascular diseases.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, or pesticides where the specific stereochemistry influences biological activity.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis to control stereoselectivity.
• Fine Chemical and Specialty Material Production: Employed in the synthesis of dyes, pigments, or liquid crystals where the amino and ester functionalities allow for further chemical modifications.
• Academic and Industrial R&D: A valuable compound for methodological studies in organic synthesis and for exploring new chemical spaces in drug discovery programs.

Basic Information

Product Name	Cyclohexanecarboxylic Acid, 1-Amino-4-Ethoxy-, Methyl Ester, cis- (9Ci)
CAS No.	203314-46-9
Molecular Formula	C11H21NO3
Molecular Weight	215.29 g/mol
Synonyms	cis-1-Amino-4-ethoxycyclohexanecarboxylic acid methyl ester; Methyl cis-1-amino-4-ethoxycyclohexanecarboxylate; (1R,4S)-1-Amino-4-ethoxycyclohexanecarboxylic acid methyl ester (enantiomer); (1S,4R)-1-Amino-4-ethoxycyclohexanecarboxylic acid methyl ester (enantiomer); 1-Amino-4-ethoxy-cyclohexanecarboxylic acid methyl ester, cis-; cis-Methyl 1-amino-4-ethoxycyclohexanecarboxylate; Cyclohexanecarboxylic acid, 1-amino-4-ethoxy-, methyl ester, cis-
EINECS	Contact for details

Quality Control

Our Cyclohexanecarboxylic Acid, 1-Amino-4-Ethoxy-, Methyl Ester, cis- (9Ci) is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure high chemical and stereochemical purity, meeting the stringent requirements for advanced synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data (HPLC, GC) and spectroscopic confirmation (NMR, IR) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and easily oxidized nature, it is recommended to store the product under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation and to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0% ee (for enantiopure grade)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.