Description

Ethyl(E)-2-((Dimethylamino)Methylene)-3-Oxobutanoate CAS NO 203186-58-7 is a versatile β-keto ester derivative featuring a dimethylaminomethylene functional group, serving as a critical building block in advanced organic synthesis. Its primary value lies in its role as a key intermediate for constructing complex heterocyclic and pharmaceutical compounds, enabling efficient multi-step synthetic routes. This high-purity intermediate is essential for research and development chemists and production facilities in the pharmaceutical, agrochemical, and fine chemical industries.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds containing pyridine, pyrimidine, or other nitrogen-containing heterocycles.
• Agrochemical Synthesis: Used in the manufacturing of advanced herbicides, fungicides, and insecticides that require complex molecular architectures.
• Fine Chemical Production: Serves as a building block for dyes, pigments, and specialty chemicals where precise molecular control is required.
• Academic & Industrial R&D: Employed in method development and discovery chemistry for creating novel chemical entities and libraries.
• Material Science: Potential intermediate in the synthesis of organic ligands for catalysts or functional materials.

Basic Information

Item	Detail
Product Name	Ethyl(E)-2-((Dimethylamino)Methylene)-3-Oxobutanoate
CAS No.	203186-58-7
Molecular Formula	C9H15NO3
Molecular Weight	185.22 g/mol
Synonyms	Ethyl (2E)-2-[(Dimethylamino)methylene]-3-oxobutanoate; Ethyl 2-[(Dimethylamino)methylene]-3-oxobutyrate; (E)-Ethyl 2-((dimethylamino)methylene)-3-oxobutanoate; 3-Oxobutyric acid, 2-[(dimethylamino)methylene]-, ethyl ester, (2E)-; Ethyl 2-(dimethylaminomethylene)-3-oxobutanoate; Acetoacetic acid, (dimethylaminomethylene)-, ethyl ester; Ethyl (E)-3-oxo-2-[(dimethylamino)methylidene]butanoate
EINECS	Contact for details

Quality Control

Our Ethyl(E)-2-((Dimethylamino)Methylene)-3-Oxobutanoate is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.