Description

2-Phenylspiro[3.3]heptane-2-carboxylic acid is a specialized spirocyclic carboxylic acid derivative, serving as a high-value synthetic intermediate in advanced organic chemistry. Its unique rigid spiro[3.3]heptane scaffold provides a three-dimensional structural motif that is crucial for modulating the physicochemical properties of target molecules. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in drug discovery and the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly those requiring constrained three-dimensional geometry to enhance binding affinity and metabolic stability.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides where the spirocyclic core can impart unique biological activity and environmental persistence profiles.
• Material Science Precursor: Serves as a monomer or functional additive in the synthesis of specialty polymers and advanced organic materials with tailored thermal or mechanical properties.
• Ligand Synthesis: Utilized in organometallic chemistry for constructing sophisticated chiral ligands used in asymmetric catalysis.
• Chemical Biology Probe Development: Acts as a core structure for creating molecular probes to study enzyme function and protein-protein interactions in biological systems.

Basic Information

Product Name	2-Phenylspiro[3.3]heptane-2-carboxylic Acid
CAS No.	202737-37-9
Molecular Formula	C15H18O2
Molecular Weight	230.30 g/mol
Synonyms	2-Phenylspiro[3.3]heptane-2-carboxylic acid; 2-Phenylspiro[3.3]heptane-2-carboxylic acid; 2-Phenylspiro[3.3]heptan-2-carboxylic acid; 2-Phenyl-2-spiro[3.3]heptanecarboxylic acid; 2-Phenyl-2-spiro[3.3]heptanecarboxylic acid; 2-Phenylspiro[3.3]heptane-2-carboxylic acid; 2-Phenylspiro[3.3]heptane-2-carboxylic acid; 2-Phenylspiro[3.3]heptane-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our 2-Phenylspiro[3.3]heptane-2-carboxylic acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis by GC. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its acidic nature, keep away from strong bases, oxidizing agents, and incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.