Description

L-Alanine, 3-Amino-, 1,1-Dimethylethyl Ester (9Ci) is a protected amino acid derivative, specifically a tert-butyl ester of 3-aminopropanoic acid. This compound is a crucial building block in organic synthesis, valued for its role in introducing the β-alanine moiety while protecting the carboxylic acid functionality. It is primarily utilized by pharmaceutical researchers and fine chemical manufacturers engaged in the development of peptides, active pharmaceutical ingredients (APIs), and other bioactive molecules.

Application

• Pharmaceutical Intermediate: A key synthon in the multi-step synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Peptide Chemistry: Serves as a protected β-alanine residue for the solid-phase or solution-phase synthesis of novel peptides and peptidomimetics.
• Bioconjugation & Linker Synthesis: Used in the preparation of chemical linkers for antibody-drug conjugates (ADCs) and other targeted therapeutics.
• Agrochemical Research: Employed as a building block in the development of new herbicides, fungicides, and plant growth regulators.
• Biochemical Research: Utilized in studies involving enzyme inhibitors, receptor ligands, and other biologically active small molecules.
• Material Science: A potential monomer or modifier in the synthesis of specialized polymers and functional materials.

Basic Information

Product Name	L-Alanine, 3-Amino-, 1,1-Dimethylethyl Ester (9Ci)
CAS No.	202477-94-9
Molecular Formula	C7H15NO2
Molecular Weight	145.20 g/mol
Synonyms	3-Aminopropanoic acid 1,1-dimethylethyl ester; tert-Butyl 3-aminopropanoate; β-Alanine tert-butyl ester; 3-Amino-propionic acid tert-butyl ester; Boc-β-Ala-OtBu (common abbreviation); (9CI)-L-Alanine, 3-amino-, 1,1-dimethylethyl ester; tert-Butyl β-alaninate
EINECS	Contact for details

Quality Control

Our production of L-Alanine, 3-Amino-, 1,1-Dimethylethyl Ester adheres to stringent quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment. We support development and commercial projects requiring material that meets GMP guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials such as strong acids and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.