Description

Ethyl 2-Cyano-2-(2,6-Difluorophenyl)Acetate is a high-value fluorinated synthetic intermediate, crucial for constructing complex molecular architectures. Its core value lies in its bifunctional cyanoacetate ester group and difluorophenyl ring, which serve as versatile building blocks for the synthesis of advanced active pharmaceutical ingredients (APIs) and agrochemicals. This compound is primarily needed by research and development chemists, process development teams, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-inflammatory agents, and kinase inhibitors.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, where the difluorophenyl moiety enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of fluorinated organic compounds for electronic materials and liquid crystals.
• Custom Synthesis and Contract Manufacturing: A critical building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	Ethyl 2-Cyano-2-(2,6-Difluorophenyl)Acetate
CAS No.	202000-98-4
Molecular Formula	C11H9F2NO2
Molecular Weight	225.19 g/mol
Synonyms	Ethyl (2,6-Difluorophenyl)(cyano)acetate; 2-Cyano-2-(2,6-difluorophenyl)acetic Acid Ethyl Ester; (2,6-Difluorophenyl)(cyano)acetic Acid Ethyl Ester; Ethyl α-Cyano-2,6-difluorophenylacetate; Acetic acid, 2-cyano-2-(2,6-difluorophenyl)-, ethyl ester; Ethyl 2-(2,6-difluorophenyl)-2-cyanoacetate
EINECS	Contact for details

Quality Control

Our Ethyl 2-Cyano-2-(2,6-Difluorophenyl)Acetate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding synthesis projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed to prevent moisture absorption and potential degradation. Store away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.