Description

Carbonic Acid 4-Amino-3-Nitro-Phenyl Ester tert-Butyl Ester (CAS NO 201811-18-9) is a specialized, high-purity chemical intermediate featuring a unique molecular architecture combining a nitroaniline derivative with a tert-butyl carbonate protecting group. This compound is critical for advanced organic synthesis, offering a protected amine functionality that is stable under a wide range of reaction conditions yet can be selectively deprotected. It is primarily sought after by research and development laboratories and fine chemical manufacturers engaged in the synthesis of complex molecules, particularly in the pharmaceutical and agrochemical sectors.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the multi-step synthesis of active pharmaceutical ingredients (APIs), especially for compounds requiring a protected aromatic amine.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides where its specific nitro and protected amine groups are integral to biological activity.
• Organic Synthesis Research: A valuable reagent in academic and industrial R&D for constructing complex heterocycles and exploring novel reaction pathways.
• Dye and Pigment Precursor: Functions as an intermediate in the synthesis of specialized azo dyes and high-performance pigments, leveraging its nitro and amino groups.
• Polymer Modification: Can be utilized to introduce functional aromatic amines into polymer backbones for creating materials with specific optical or electronic properties.
• Chemical Biology Probes: Employed in the development of molecular probes and linkers where a cleavable tert-butyloxycarbonyl (Boc)-like group is required.

Basic Information

Product Name	Carbonic Acid 4-Amino-3-Nitro-Phenyl Ester tert-Butyl Ester
CAS No.	201811-18-9
Molecular Formula	C11H14N2O5
Molecular Weight	254.24 g/mol
Synonyms	tert-Butyl (4-amino-3-nitrophenyl) carbonate; 4-Amino-3-nitrophenyl tert-butyl carbonate; 3-Nitro-4-aminophenyl tert-butyl carbonate; tert-Butoxycarbonyloxy-4-amino-3-nitrobenzene; Boc-4-amino-3-nitrophenol; 4-(tert-Butoxycarbonyloxy)-2-nitroaniline; 2-Nitro-4-(tert-butoxycarbonyloxy)aniline; 201811-18-9
EINECS	Contact for details

Quality Control

Our production of Carbonic Acid 4-Amino-3-Nitro-Phenyl Ester tert-Butyl Ester adheres to stringent quality management protocols. Each batch is characterized and tested using advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality system is designed to support cGMP (current Good Manufacturing Practice) requirements for pharmaceutical intermediates, ensuring traceability and reliability for our global clientele.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is easily oxidized and should be handled and stored under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, open flames, and incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.