Description

5-Cholesten-3-Ol 6-[(7-Nitro-2-1,3-Benzoxadiazol-4-Yl)Amino]Caproate is a specialized fluorescent cholesterol derivative, a critical tool compound for advanced biomedical research. Its core value lies in its ability to act as a fluorescent probe, enabling the visualization and tracking of cholesterol metabolism and transport in cellular systems. This compound is essential for researchers in the fields of lipid biology, cell signaling, and the study of diseases like atherosclerosis and Niemann-Pick type C.

Application

• Fluorescent Labeling Agent: Used as a vital probe for labeling and visualizing cholesterol and its analogs in live-cell imaging and fluorescence microscopy studies.
• Lipid Raft & Membrane Dynamics Research: Essential for investigating the organization, trafficking, and function of lipid rafts and plasma membrane domains.
• Intracellular Cholesterol Transport Studies: A key tool for tracking the movement and distribution of cholesterol within cells, aiding in the study of metabolic pathways.
• Drug Discovery & Screening: Employed in high-throughput assays to identify compounds that modulate cholesterol homeostasis and related cellular processes.
• Biochemical Assay Development: Serves as a standard or reagent in developing sensitive assays for cholesterol-binding proteins and enzymes.
• Academic & Pharmaceutical R&D: Critical for basic research in universities and applied research in pharmaceutical companies focusing on cardiovascular and metabolic diseases.

Basic Information

Product Name	5-Cholesten-3-Ol 6-[(7-Nitro-2-1,3-Benzoxadiazol-4-Yl)Amino]Caproate
CAS No.	201731-19-3
Molecular Formula	C40H59N3O5
Molecular Weight	661.92 g/mol
Synonyms	NBD-Cholesterol; 22-NBD-Cholesterol; 6-[(7-Nitro-2-1,3-benzoxadiazol-4-yl)amino]hexanoic Acid Cholesteryl Ester; NBD C6-Cholesterol; Cholesteryl 6-((7-Nitrobenzo[c][1,2,5]oxadiazol-4-yl)amino)hexanoate; Fluorescent Cholesterol Derivative; NBD-labeled Cholesterol
EINECS	Contact for details

Quality Control

Our 5-Cholesten-3-Ol 6-[(7-Nitro-2-1,3-Benzoxadiazol-4-Yl)Amino]Caproate is produced under strict quality management protocols to ensure the high purity and batch-to-batch consistency required for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and fluorescence properties. We support research compliance with traceable documentation.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccant. This compound is both light-sensitive (store away from light) and hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	Orange to red solid or film
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥ 95%
Fluorescence Properties	Ex/Em ~465/535 nm (in methanol)
Solubility	Soluble in DMSO, DMF, chloroform; sparingly soluble in alcohols

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.