Description

2H-Cyclopenta[B]Furan-4-Carboxaldehyde, Hexahydro-2-Oxo-, [3Ar-(3Aalpha,4Alpha,6Aalpha)]- (9Ci) is a specialized bicyclic organic compound featuring a fused cyclopentane and furanone structure, serving as a valuable chiral building block and synthetic intermediate. Its defined stereochemistry and functional groups make it a critical precursor for the synthesis of complex molecules in advanced research and development. This compound is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers for applications in medicinal chemistry, including the development of novel active pharmaceutical ingredients (APIs) and other high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry: Used in structure-activity relationship (SAR) studies and the synthesis of complex heterocyclic compounds for biological screening.
• Asymmetric Synthesis: Serves as a building block in stereoselective synthesis due to its defined [3Ar-(3Aalpha,4Alpha,6Aalpha)]- configuration.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances requiring specific stereochemistry.
• Academic & Industrial Research: A valuable reagent for methodological development in organic synthesis and catalysis research.

Basic Information

Product Name	2H-Cyclopenta[B]Furan-4-Carboxaldehyde, Hexahydro-2-Oxo-, [3Ar-(3Aalpha,4Alpha,6Aalpha)]- (9Ci)
CAS No.	201421-82-1
Molecular Formula	C8H10O3
Molecular Weight	154.16 g/mol
Synonyms	Hexahydro-2-oxo-2H-cyclopenta[b]furan-4-carboxaldehyde; (3aR,4R,6aS)-Hexahydro-2-oxo-2H-cyclopenta[b]furan-4-carbaldehyde; 4-Formylhexahydro-2-oxo-2H-cyclopenta[b]furan; (3aR,4R,6aS)-4-Formylhexahydro-2H-cyclopenta[b]furan-2-one; 2H-Cyclopenta[b]furan-4-carboxaldehyde, hexahydro-2-oxo-, (3aR,4R,6aS)-; (3aR,4R,6aS)-Hexahydro-2-oxocyclopenta[b]furan-4-carbaldehyde
EINECS	Contact for details

Quality Control

Our 2H-Cyclopenta[B]Furan-4-Carboxaldehyde, Hexahydro-2-Oxo-, [3Ar-(3Aalpha,4Alpha,6Aalpha)]- (9Ci) is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure high chemical and stereochemical purity suitable for demanding synthetic applications. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.