Description

3 6-Di-o-(Triisopropylsilyl)-D-Glucal is a high-value, protected carbohydrate intermediate, specifically a silyl ether derivative of D-glucal. This compound is essential for synthetic chemists as it provides a versatile and reactive scaffold for the stereoselective construction of complex glycosidic linkages and other chiral molecules. It is primarily utilized in advanced pharmaceutical research and development, particularly in the synthesis of nucleoside analogs, antiviral agents, and other bioactive carbohydrate-based compounds.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel nucleoside and nucleotide analogs for antiviral and anticancer drug discovery.
• Glycosylation Reactions: Serves as a glycosyl donor or acceptor in the stereocontrolled synthesis of oligosaccharides and complex glycoconjugates.
• Chiral Pool Synthesis: Used as a chiral template for the preparation of enantiomerically pure natural products and fine chemicals.
• Carbohydrate Chemistry Research: An essential reagent for academic and industrial research focused on developing new synthetic methodologies in glycoscience.
• Protecting Group Strategy: The triisopropylsilyl (TIPS) groups provide orthogonal protection for hydroxyl functions in multi-step organic synthesis.

Basic Information

Product Name	3 6-Di-o-(Triisopropylsilyl)-D-Glucal
CAS No.	201053-37-4
Molecular Formula	C24H50O5Si2
Molecular Weight	474.83 g/mol
Synonyms	3,6-Bis-O-(triisopropylsilyl)-D-glucal; 1,5-Anhydro-3,6-bis-O-[(triisopropylsilyl)]-2-deoxy-D-arabino-hex-1-enitol; D-Glucal, 3,6-bis-O-(triisopropylsilyl)-; 3,6-Di-O-triisopropylsilyl-D-glucal; TIPS-protected D-glucal; 3,6-Di-O-TIPS-D-glucal; 1,5-Anhydro-3,6-di-O-(triisopropylsilyl)-2-deoxy-D-arabino-hex-1-enitol
EINECS	Contact for details

Quality Control

Our 3 6-Di-o-(Triisopropylsilyl)-D-Glucal is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to relevant industry standards for fine chemical intermediates, ensuring reliable performance in sensitive synthetic sequences.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to maintain stability and prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.