Description

1,2-Cyclohexanedicarboxylic Acid, 1-Methyl Ester, (1S,2S)- is a high-purity, stereochemically defined chiral building block. This compound matters as a critical intermediate for synthesizing advanced pharmaceuticals, agrochemicals, and specialty polymers where its specific (1S,2S) configuration imparts desired biological activity or material properties. It is needed by R&D chemists and process development teams in the pharmaceutical, fine chemical, and advanced materials industries seeking to develop novel, high-value products with precise stereochemistry.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in developing cardiovascular, neurological, and anti-inflammatory drugs.
• Agrochemical Synthesis: Used in the production of advanced, enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Polymer Modification: Employed to introduce chiral centers and functional groups into specialty polymers, influencing their physical and optical properties.
• Fine Chemical Research: A valuable reagent in academic and industrial R&D for exploring new synthetic methodologies and creating complex molecular architectures.
• Flavor and Fragrance Industry: Potential intermediate for the synthesis of stereospecific aroma chemicals.

Basic Information

Item	Detail
Product Name	1,2-Cyclohexanedicarboxylic Acid, 1-Methyl Ester, (1S,2S)-
CAS No.	200948-89-6
Molecular Formula	C9H14O4
Molecular Weight	186.21 g/mol
Synonyms	(1S,2S)-1-Methyl Cyclohexane-1,2-dicarboxylate; (1S,2S)-Methyl Hydrogen Cyclohexane-1,2-dicarboxylate; (1S,2S)-1-Carbomethoxycyclohexane-2-carboxylic Acid; (1S,2S)-Cyclohexane-1,2-dicarboxylic Acid Monomethyl Ester; (1S,2S)-CHDA Monomethyl Ester; (1S,2S)-1,2-CHDA-MME; (1S,2S)-Hexahydrophthalic Acid Monomethyl Ester; Stereoisomer of Methyl Hydrogen Hexahydrophthalate
EINECS	Contact for details

Quality Control

Our 1,2-Cyclohexanedicarboxylic Acid, 1-Methyl Ester, (1S,2S)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.