Description

(R)-(+)-2-Butylbutanedioic Acid 4-tert-Butyl Ester is a high-purity chiral intermediate of significant importance in asymmetric synthesis. This compound is valued for its role in constructing complex molecular architectures with defined stereochemistry. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral building block in the synthesis of enantiomerically pure drugs and bioactive molecules.
• Asymmetric Synthesis: Used as a starting material or reagent in catalytic and stoichiometric asymmetric transformations.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals requiring high stereochemical fidelity.
• Academic & Industrial Research: Serves as a valuable compound for methodological development in organic and medicinal chemistry.
• Ligand and Catalyst Preparation: Can be utilized in the synthesis of chiral ligands for metal-catalyzed reactions.

Basic Information

Item	Details
Product Name	(R)-(+)-2-Butylbutanedioic Acid 4-tert-Butyl Ester
CAS No.	200866-61-1
Molecular Formula	C12H22O4
Molecular Weight	230.30 g/mol
Synonyms	(R)-4-(tert-Butoxy)-4-oxo-2-butylbutanoic Acid; (R)-2-Butylsuccinic Acid 4-tert-Butyl Ester; (R)-(+)-2-Butylsuccinic Acid Mono-tert-butyl Ester; (3R)-3-(2-Carboxyethyl)heptanoic Acid tert-Butyl Ester; (R)-Mono-tert-butyl 2-butylsuccinate; (R)-1-tert-Butyl 4-hydrogen 2-butylsuccinate; (R)-4-(tert-Butoxycarbonyl)heptanoic Acid
EINECS	Contact for details

Quality Control

Our (R)-(+)-2-Butylbutanedioic Acid 4-tert-Butyl Ester is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) detailing identity, purity, and enantiomeric excess are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if necessary.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.