Description

Fmoc-D-Asn-Opfp CAS NO 200193-34-6 is a protected amino acid derivative, specifically the pentafluorophenyl (OPfp) ester of N-α-Fmoc-D-asparagine. This compound is a critical building block in solid-phase peptide synthesis (SPPS), enabling the efficient and racemization-free incorporation of the D-asparagine residue into peptide chains. It is essential for research and production in pharmaceutical development, biotechnology, and advanced materials science, where precise stereochemistry and high coupling efficiency are paramount.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key reagent for the automated synthesis of peptides containing D-asparagine.
• Pharmaceutical Intermediates: Used in the research and development of therapeutic peptides, including hormone analogs and enzyme inhibitors.
• Bioconjugation: Serves as an activated ester for labeling proteins or other biomolecules under mild conditions.
• Combinatorial Chemistry: Employed in libraries for drug discovery to create diverse peptide-based compounds.
• Academic & Industrial Research: Fundamental building block for studying peptide structure, function, and stability.
• Production of Chiral Compounds: Utilized in the synthesis of non-natural peptides and peptidomimetics for advanced material and catalyst design.

Basic Information

Product Name	Fmoc-D-Asn-Opfp
CAS No.	200193-34-6
Molecular Formula	C26H19F5N2O6
Molecular Weight	550.44 g/mol
Synonyms	Fmoc-D-asparagine pentafluorophenyl ester; N-α-Fmoc-D-asparagine OPfp ester; (2R)-2-[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]-4-oxo-4-(pentafluorophenoxy)butanoic acid; Fmoc-D-Asn-OPfp; Fmoc-D-Asparagine-OPfp; Fmoc-D-Asn-OPh(CF3)2; N-Fmoc-D-asparagine pentafluorophenyl ester; D-Asn(Fmoc)-OPfp
EINECS	Contact for details

Quality Control

Our Fmoc-D-Asn-Opfp is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, chiral analysis to confirm stereochemical integrity, and NMR for structural confirmation. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are available upon request to ensure compliance with your research and production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a freezer at -20°C to -10°C under desiccant. This product is hygroscopic (moisture-sensitive) and light-sensitive. Allow the sealed container to equilibrate to room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥98.0%
Optical Rotation	Contact for details
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.