Description

1-Azetidinecarboxylic Acid, 2-Formyl-, 1,1-Dimethylethyl Ester, (2S)- is a high-purity, chiral azetidine derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its role in constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs). It is primarily sought by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for creating new therapeutic agents and functional materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of protease inhibitors, enzyme modulators, and other bioactive molecules.
• Peptidomimetics Research: Used to incorporate constrained azetidine scaffolds into peptide analogs to enhance metabolic stability and binding affinity.
• Agrochemical Development: Serves as a precursor in creating novel herbicides, fungicides, and plant growth regulators with specific stereochemistry.
• Ligand and Catalyst Synthesis: Employed in the preparation of chiral ligands for asymmetric catalysis and organometallic complexes.
• Material Science: Utilized in the development of specialty polymers and functionalized surfaces requiring specific stereochemical orientation.
• Academic & Contract Research: A valuable reagent for methodological studies in organic chemistry and medicinal chemistry programs.

Basic Information

Product Name	1-Azetidinecarboxylic Acid, 2-Formyl-, 1,1-Dimethylethyl Ester, (2S)-
CAS No.	200184-45-8
Molecular Formula	C9H15NO3
Molecular Weight	185.22 g/mol
Synonyms	(2S)-2-Formylazetidine-1-carboxylic acid tert-butyl ester; tert-Butyl (2S)-2-formylazetidine-1-carboxylate; (S)-1-Boc-2-formylazetidine; (S)-N-Boc-2-formylazetidine; (S)-2-Formyl-1-(tert-butoxycarbonyl)azetidine; (S)-1-(tert-Butoxycarbonyl)-2-formylazetidine; Boc-Azetidine-2-carboxaldehyde, (S)-; Azetidine-1-carboxylic acid, 2-formyl-, 1,1-dimethylethyl ester, (2S)-
EINECS	Contact for details

Quality Control

Our 1-Azetidinecarboxylic Acid, 2-Formyl-, 1,1-Dimethylethyl Ester, (2S)- is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high chemical purity. All products undergo rigorous analytical testing, including chiral HPLC to confirm enantiomeric excess and identity confirmation by spectroscopic methods. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under inert atmosphere (e.g., nitrogen or argon) when appropriate to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid or clear to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.