Description

Methyl 2-O,3-o-Diacetyl-4-o-(p-Tolylsulfonyl)-β-L-Arabinopyranoside is a high-purity, protected arabinose derivative, a critical building block in synthetic organic chemistry. Its value lies in its role as a key chiral intermediate for the synthesis of complex nucleosides, antiviral agents, and other biologically active compounds. This product is essential for research and development laboratories, pharmaceutical manufacturers, and fine chemical producers requiring precise stereochemistry and functional group manipulation.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel nucleoside analogues with potential antiviral or anticancer activity.
• Carbohydrate Chemistry Research: Serves as a protected glycosyl donor or acceptor for constructing complex oligosaccharides and glycoconjugates.
• Glycosylation Reactions: Used in the development of new glycosylation methodologies due to its activated sulfonyl ester group.
• Pro-drug Synthesis: Employed in the design and synthesis of pro-drug forms of nucleoside-based therapeutics to enhance bioavailability.
• Chiral Pool Synthesis: Provides a source of the L-arabinose configuration for the asymmetric synthesis of natural products and specialty chemicals.
• Biochemical Tool Development: Utilized in creating labeled or modified sugars for metabolic pathway studies and enzyme inhibition assays.

Basic Information

Product Name	Methyl 2-O,3-o-Diacetyl-4-o-(p-Tolylsulfonyl)-β-L-Arabinopyranoside
CAS No.	29919-81-1
Molecular Formula	C₁₇H₂₂O₉S
Molecular Weight	402.42 g/mol
Synonyms	Methyl 2,3-Di-O-acetyl-4-O-(p-tolylsulfonyl)-β-L-arabinopyranoside; Methyl 2,3-Di-O-acetyl-4-O-tosyl-β-L-arabinopyranoside; 4-O-Tosyl-2,3-di-O-acetyl-β-L-arabinopyranoside methyl glycoside; β-L-Arabinopyranoside, methyl 2,3-di-O-acetyl-4-O-[(4-methylphenyl)sulfonyl]-; Methyl 4-O-tosyl-2,3-di-O-acetyl-β-L-arabinopyranoside; Tosylated L-Arabinose Derivative; Protected L-Arabinose Methyl Glycoside
EINECS	Contact for details

Quality Control

Every batch of Methyl 2-O,3-o-Diacetyl-4-o-(p-Tolylsulfonyl)-β-L-Arabinopyranoside is manufactured under strict quality management systems and undergoes comprehensive analytical testing. Our products are guaranteed to meet the high-purity standards required for research and pharmaceutical applications. A detailed Certificate of Analysis (COA) confirming identity, purity, and impurity profiles by HPLC, NMR, and other relevant techniques is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.