Description

Cyclobutanecarboxylic Acid, 1-Amino-3,3-Dimethyl- (8Ci,9Ci) is a specialized, high-purity organic building block featuring a unique constrained cyclobutane ring system. This compound matters as a critical chiral intermediate for the synthesis of complex pharmaceutical molecules and advanced materials, offering a distinct structural motif for drug discovery. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional compounds. CAS No. 29810-92-2.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring constrained ring systems.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides with tailored biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis.
• Peptidomimetics Research: The 1-amino-3,3-dimethyl cyclobutane carboxylic acid structure is valuable for constructing conformationally restricted peptide analogs in medicinal chemistry.
• Material Science Monomer: Potential use as a building block for novel polymers and dendrimers with specific thermal or mechanical properties.
• Chemical Biology Probes: Employed in the synthesis of molecular probes and tags for studying biological systems and enzyme mechanisms.

Basic Information

Product Name	Cyclobutanecarboxylic Acid, 1-Amino-3,3-Dimethyl- (8Ci,9Ci)
CAS No.	29810-92-2
Molecular Formula	C7H13NO2
Molecular Weight	143.18 g/mol
Synonyms	1-Amino-3,3-dimethylcyclobutanecarboxylic acid; 3,3-Dimethyl-1-aminocyclobutanecarboxylic acid; (1-Amino-3,3-dimethylcyclobutyl)formic acid; 1-AADCB; 29810-92-2; Cyclobutanecarboxylic acid, 1-amino-3,3-dimethyl-; 1-Amino-3,3-dimethylcyclobutan-1-carboxylic acid
EINECS	Contact for details

Quality Control

Our Cyclobutanecarboxylic Acid, 1-Amino-3,3-Dimethyl- is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data (HPLC, GC) and spectroscopic confirmation (NMR, IR) are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.