Description

(1S)-1α-(β-D-Glucopyranosyloxy)-1,4A,5,7Aα-Tetrahydro-4Aα-Hydroxy-7-(Hydroxymethyl)Cyclopenta[C]Pyran-4-Carboxylic Acid is a high-purity, complex glycosidic compound of significant interest in advanced pharmaceutical and biochemical research. Its intricate molecular structure, featuring a cyclopenta[c]pyran core linked to a glucose moiety, makes it a valuable intermediate or reference standard for developing novel therapeutic agents. This compound is primarily sought by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in synthetic chemistry and drug discovery programs.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly in steroid or terpenoid-related pathways.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies to investigate glycosidase or glycosyltransferase activity and mechanisms.
• Reference Standard: Employed as a high-purity analytical standard for quality control (QC) and method development in HPLC, LC-MS, or NMR analysis within pharmaceutical quality assurance.
• Medicinal Chemistry: Acts as a core scaffold for structure-activity relationship (SAR) studies aimed at discovering new drugs with anti-inflammatory, antiviral, or anticancer properties.
• Fine Chemical Synthesis: Utilized in multi-step organic synthesis for the preparation of specialized natural product analogs or novel chemical entities.

Basic Information

Product Name	(1S)-1α-(β-D-Glucopyranosyloxy)-1,4A,5,7Aα-Tetrahydro-4Aα-Hydroxy-7-(Hydroxymethyl)Cyclopenta[C]Pyran-4-Carboxylic Acid
CAS No.	29781-29-1
Molecular Formula	C16H22O10
Molecular Weight	374.34 g/mol
Synonyms	1α-(β-D-Glucopyranosyloxy)-1,4a,5,7a-tetrahydro-4aα-hydroxy-7-(hydroxymethyl)cyclopenta[c]pyran-4-carboxylic acid; Cyclopenta[c]pyran-4-carboxylic acid, 1,4a,5,7a-tetrahydro-1-(β-D-glucopyranosyloxy)-4a-hydroxy-7-(hydroxymethyl)-, (1S,4aR,7aS)-; Glucosyl cyclopentapyran carboxylic acid derivative; (1S,4aR,7aS)-1-(β-D-Glucopyranosyloxy)-1,4a,5,7a-tetrahydro-4a-hydroxy-7-(hydroxymethyl)cyclopenta[c]pyran-4-carboxylic acid; A glycosylated cyclopentapyran carboxylic acid. Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our (1S)-1α-(β-D-Glucopyranosyloxy)-1,4A,5,7Aα-Tetrahydro-4Aα-Hydroxy-7-(Hydroxymethyl)Cyclopenta[C]Pyran-4-Carboxylic Acid is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and structural confirmation via NMR and MS. Our products are designed to meet the stringent requirements of pharmaceutical R&D and reference standard applications. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.