Description

Triglutamate Folate is a conjugated form of folic acid, where three glutamic acid residues are linked to the pteridine moiety. This specific molecular structure offers distinct stability and bioavailability advantages, making it a critical intermediate and active ingredient in advanced nutritional and pharmaceutical formulations. It is essential for manufacturers in the nutraceutical, pharmaceutical, and food fortification sectors seeking a reliable, high-purity folate source for specialized applications.

Application

• Pharmaceutical Intermediates: Serves as a key precursor in the synthesis of specialized folate-based drugs and high-potency prescription supplements.
• Advanced Nutraceuticals: Used in the formulation of premium dietary supplements targeting specific metabolic pathways where enhanced folate delivery is required.
• Clinical Nutrition: Incorporated into medical food products and enteral formulas designed for patients with specific nutritional deficiencies or absorption issues.
• Biochemical Research: Employed as a standard or reagent in folate metabolism studies, enzymatic assays, and cellular nutrition research.
• Food Fortification (Specialized): Potential use in stabilizing folate content in functional foods and beverages, though application depends on specific regulatory approval.
• Cosmeceutical Ingredients: Explored for use in topical formulations aimed at supporting skin health at a cellular level.

Basic Information

Item	Detail
Product Name	Triglutamate Folate
CAS No.	29701-38-0
Molecular Formula	C26H31N9O9
Molecular Weight	601.59 g/mol
Synonyms	Pteroyltriglutamic Acid; Folinic Acid-SF; N5-Formyl-5,6,7,8-tetrahydrofolic Acid Triglutamate; 5-Formyl-THF-Glu3; Leucovorin Triglutamate; (6S)-5-Formyl-5,6,7,8-tetrahydrofolic Acid Triglutamate; Citrovorum Factor Triglutamate
EINECS	Contact for details

Quality Control

Our Triglutamate Folate is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and assay, to ensure it meets stringent specifications for pharmaceutical and nutraceutical use. Certificates of Analysis (COA) documenting identity, purity, and related substances are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.