Description

1-Acetoxy-2-Fluorobenzene is a versatile fluorinated aromatic ester, serving as a key synthetic intermediate in advanced organic chemistry. Its value lies in providing a protected phenolic functionality with an ortho-fluorine substituent, enabling selective derivatization for complex molecule construction. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial building block for synthesizing fluorinated drug candidates, particularly in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides where the fluorine atom enhances biological activity and stability.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for creating fluorinated aromatic cores in electronic display and lighting technologies.
• Polymer Modification: Employed to introduce fluorophenol segments into polymer backbones, altering thermal and chemical resistance properties.
• Organic Synthesis Reagent: Acts as a protected fluorophenol equivalent in multi-step synthesis, including cross-coupling and nucleophilic substitution reactions.
• Dye & Pigment Intermediate: Utilized in the synthesis of specialized fluorinated colorants with improved lightfastness and solubility.

Basic Information

Product Name	1-Acetoxy-2-Fluorobenzene
CAS No.	29650-44-0
Molecular Formula	C8H7FO2
Molecular Weight	154.14 g/mol
Synonyms	2-Fluorophenyl acetate; o-Fluorophenyl acetate; Acetic acid 2-fluorophenyl ester; 2-Fluorophenol acetate; 1-Fluoro-2-acetoxybenzene; Fluorophenyl acetate; (2-Fluorophenyl) acetate
EINECS	Contact for details

Quality Control

Our 1-Acetoxy-2-Fluorobenzene is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure high chemical purity and identity. A Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment. We support cGMP compliance for pharmaceutical applications and can tailor specifications to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases, strong oxidizing agents, and heat sources. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Clear colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC/HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.